{"id":25364,"date":"2023-04-20T11:16:47","date_gmt":"2023-04-20T09:16:47","guid":{"rendered":"https:\/\/www.l3s.de\/?page_id=25364"},"modified":"2025-09-01T14:45:26","modified_gmt":"2025-09-01T12:45:26","slug":"p4d","status":"publish","type":"page","link":"https:\/\/www.l3s.de\/de\/research-at-l3s\/all-projects\/project-archive\/p4d\/","title":{"rendered":"P4D"},"content":{"rendered":"
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n\n\"\"\n
<\/div>\n<\/div>\n<\/div>\n<\/div>\n
<\/div>\n
\n
\n
\n
\n
\n
\n
\n\nStart:\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
\n
\n
\n
\n\n01.09.2022\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
\n
\n
\n
\n
\n
\n\nEnde:\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
\n
\n
\n
\n\n30.08.2025\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
\n
\n
\n
\n
\n
\n\nWebseite:\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
\n
\n
\n
gesundheitsforschung-bmbf.de…<\/a>\n<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
\n
\n
<\/div>\n
\n
\n
\n
\n
\n
\n
\n

P4D<\/h2>\n<\/div>\n<\/div>\n
\n
\n\nAssoziationsstudien und Datenplattform f\u00fcr elektronische Gesundheitsakten und Omics-Daten\n\n<\/div>\n<\/div>\n
<\/div>\n
\n
\n\nDepressive disorders are among the most common psychiatric disorders in Europe. Despite the large number of available treatments, only a proportion of people with depression benefit from long-term treatment. Although there\nis considerable evidence that there are subgroups of patients who respond particularly well to certain treatments, there are no established markers for these subgroups.\n\nThe integrated research platform P4D aims to investigate these subgroups in order to improve diagnosis, treatment and prevention of depressive disorders through personalised treatment approaches. To this end, an already identified\nblood marker of antidepressant response will be clinically tested and validated for use in clinical practice. In addition, a large cohort of patients with depressive disorders will be recruited and subjected to deep phenotyping\nand genotyping to identify new subtypes of depression from the analysis of the extensive data using machine learning methods. On this basis, publicly available, innovative decision support tools will be developed to enable\npersonalised treatment.\n\nTo this end, Leibniz Universit\u00e4t Hannover (LUH) is establishing a system for the secure storage, processing, management and transmission of electronic health records and omics data from the P4D cohort. Novel approaches to\nraw data compression will be explored to optimise storage, processing and transmission costs. In addition, the LUH is involved in the overall data analysis of the platform to characterise prognostic depression subtypes\nidentified by systems medicine approaches. In particular, new machine learning methods will be developed to generate molecular signatures. The research platform is coordinated by the Hannover Medical School and has a total\nof ten project partners.\n\n<\/div>\n<\/div>\n
<\/div>\n
\n
\n\nF\u00f6rderprogramm<\/a>\n
<\/span><\/div>\n
<\/span><\/div>\n
\n
\n
\n
\n\n–\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n\nProjektpartner<\/a>\n
<\/span><\/div>\n
<\/span><\/div>\n
\n
\n
\n
\n\n–\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
\n
\n
\n
\n
\n
\n

Kontakt<\/h1>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
\n
\n
\n
\n
\n\n\"\"\n
<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
\n

Prof. Dr.-Ing. J\u00f6rn Ostermann<\/h4>\n<\/div>\n<\/div>\n
\n
\n\nProjektmanager\n\n<\/div>\n<\/div>\n
\n
\n
\n
\n
\n
\n
<\/span> ostermann@l3s.de<\/a>\n<\/span><\/div>\n<\/div>\n
\n
<\/span> +49 511 762-5316<\/a>\n<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

Start: 01.09.2022 End: 30.08.2025 Website: gesundheitsforschung-bmbf.de… P4D Association studies and data platform for electronic health records and omics data Depressive disorders are among the most common psychiatric disorders in Europe. Despite the large number of available treatments, only a proportion of people with depression benefit from long-term treatment. Although there is considerable evidence that there […]<\/p>","protected":false},"author":7,"featured_media":26386,"parent":10129,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/full-width-page.php","meta":{"_acf_changed":false,"footnotes":""},"categories":[75],"tags":[119],"class_list":["post-25364","page","type-page","status-publish","has-post-thumbnail","hentry","category-project-archive","tag-archive"],"acf":[],"aioseo_notices":[],"publishpress_future_action":{"enabled":false,"date":"2026-05-21 10:48:21","action":"category","newStatus":"draft","terms":[75],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/pages\/25364","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/comments?post=25364"}],"version-history":[{"count":1,"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/pages\/25364\/revisions"}],"predecessor-version":[{"id":40718,"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/pages\/25364\/revisions\/40718"}],"up":[{"embeddable":true,"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/pages\/10129"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/media\/26386"}],"wp:attachment":[{"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/media?parent=25364"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/categories?post=25364"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.l3s.de\/de\/wp-json\/wp\/v2\/tags?post=25364"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}