What will tomorrow's medicine look like? Digitalization is also bringing about major changes in the healthcare industry. Huge amounts of data, such as genetic information or medical images, are generated every day. The analysis and interpretation of these data should make healthcare better, safer and more cost-efficient. To ensure that this does not remain wishful thinking, scientists at the L3S, together with partners from medical research, are making a contribution to the beneficial use of big data in medicine. But L3S researchers are also active in other medical fields. In the fifth issue of the L3S magazine Binaire, we present a large number of research projects at the L3S in the field of medicine.